Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7758695 | 0.89 | MAPK1 (0.51) | NOTUMMAPK1CETPGPR35TACR1 | |
| SCHEMBL21061047 | 0.88 | NOTUM (0.50) | NOTUMMAPK1CETPACP1GPR35 | |
| SCHEMBL28406891 | 0.83 | MAPK1 (0.47) | NOTUMMAPK1CETPGPR35TACR1 | |
| SCHEMBL21137742 | 0.80 | NOTUM (0.46) | NOTUMACP1TAS2R14GPR35TACR1 | |
| SCHEMBL21061045 | 0.79 | TAS2R14 (0.45) | NOTUMTAS2R14TACR1 | |
| SCHEMBL21061048 | 0.78 | NOTUM (0.44) | NOTUMACP1TAS2R14GPR35TACR1 | |
| SCHEMBL15018577 | 0.76 | CES2 (0.51) | MAPK1ALDH1A1MAPT | |
| SCHEMBL30368489 | 0.76 | CES2 (0.51) | MAPK1ALDH1A1MAPT | |
| SCHEMBL24037032 | 0.76 | NOTUM (0.50) | NOTUMCETPACP1TAS2R14GPR35 | |
| SCHEMBL25677270 | 0.76 | NOTUM (0.74) | NOTUMCETPACP1TAS2R14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019115404-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-20 | — | — | WO | disclosed |