SCHEMBL21138263

SCHEMBL21138263

CCCCOC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(=O)CCC

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.70
▸ PYGB P11216 1/20 0.54
▸ CA1 P00915 2/20 0.51
▸ CA2 P00918 2/20 0.51
▸ CA9 Q16790 2/20 0.51
▸ LGALS8 O00214 1/20 0.48
▸ LGALS3 P17931 1/20 0.48
▸ LGALS4 P56470 1/20 0.48
▸ ALDH1A1 P00352 2/20 0.47
▸ THRB P10828 1/20 0.47
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ B4GALT1 P15291 1/20 0.44
▸ TLR4 O00206 4/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ LY96 Q9Y6Y9 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21137864 0.90 PYGB (0.59) MAPK1PYGBCA1CA2CA9
SCHEMBL24943521 0.87 MAPK1 (0.90) MAPK1CA1CA2CA9LGALS8
SCHEMBL28256795 0.87 MAPK1 (0.90) MAPK1CA1CA2CA9LGALS8
SCHEMBL14010278 0.87 MAPK1 (0.90) MAPK1CA1CA2CA9LGALS8
SCHEMBL13786399 0.87 MAPK1 (0.90) MAPK1CA1CA2CA9LGALS8
SCHEMBL9521910 0.87 MAPK1 (0.69) MAPK1PYGBCA1CA2CA9
SCHEMBL22886810 0.84 MAPK1 (0.72) MAPK1PYGBCA1CA2CA9
SCHEMBL22927888 0.84 MAPK1 (0.97) MAPK1CA1CA2CA9LGALS8
SCHEMBL2733582 0.84 MAPK1 (0.97) MAPK1CA1CA2CA9LGALS8
SCHEMBL14010316 0.84 MAPK1 (0.97) MAPK1CA1CA2CA9LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-02-28 — — US disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, GLA MAPK1 887/4885PYGB 760/4885CA1 3104/4885
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, GLA MAPK1 887/4885PYGB 760/4885CA1 3104/4885
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA MAPK1 846/4885PYGB 601/4885CA1 3238/4885
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA MAPK1 846/4885PYGB 601/4885CA1 3238/4885
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof OGT, UGGT1, GLA MAPK1 846/4885PYGB 601/4885CA1 3238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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