Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK1 | P51617 | 3/20 | 0.42 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CLK3 | P49761 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30587040 | 0.72 | IRAK1 (0.50) | IRAK1TRPC5ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL22573000 | 0.71 | FYN (0.44) | IRAK1PIM1 | |
| SCHEMBL21163853 | 0.68 | MAPT (0.42) | TRPC5KDM4EALDH1A1EGLN2PIK3C2B | |
| SCHEMBL12176285 | 0.68 | MAPT (0.42) | TRPC5KDM4EALDH1A1EGLN2PIK3C2B | |
| SCHEMBL17115796 | 0.67 | — | — | |
| SCHEMBL22026611 | 0.67 | CCNT1 (0.37) | IRAK1TRPC5CCNT1KCNH3 | |
| SCHEMBL25731567 | 0.66 | DDB1 (0.41) | IRAK1SMN1; SMN2IRAK4LRRK2 | |
| SCHEMBL19923108 | 0.66 | CCNT1 (0.43) | IRAK1TRPC5PIM1PIM2MAOB | |
| SCHEMBL17852320 | 0.66 | TRPC5 (0.48) | TRPC5KDM4EALDH1A1SMN1; SMN2EGLN2 | |
| SCHEMBL28916334 | 0.65 | HRH4 (0.36) | IRAK1TRPC5PIM1EGLN2PIK3C2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392138-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-17 | — | — | US | disclosed |
| US-20200392138-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-17 | — | — | US | disclosed |
| WO-2019115404-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392138-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | DDT, ACHE, MNS1 | IRAK1 4745/4885TRPC5 399/4885PIM1 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.