Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21122190 | 1.00 | ESR2 (0.32) | ESR2ALDH1A1IDO1TDO2 | |
| SCHEMBL17203791 | 0.90 | — | — | |
| SCHEMBL22203273 | 0.83 | — | — | |
| SCHEMBL20298979 | 0.82 | WDR5 (0.39) | ALDH1A1 | |
| SCHEMBL20298764 | 0.82 | WDR5 (0.36) | ALDH1A1 | |
| SCHEMBL20789238 | 0.81 | FPR3 (0.38) | ESR2IDO1TDO2 | |
| SCHEMBL20789235 | 0.81 | FPR3 (0.38) | ESR2IDO1TDO2 | |
| SCHEMBL20789138 | 0.81 | — | — | |
| SCHEMBL20789141 | 0.81 | — | — | |
| SCHEMBL20807215 | 0.81 | WDR5 (0.39) | ALDH1A1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220056022-A1 | RAD51 INHIBITORS | CYTEIR THERAPEUTICS, INC. | 2022-02-24 | — | — | US | disclosed |
| US-20190194182-A1 | RAD51 INHIBITORS | CYTEIR THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220056022-A1 | RAD51 INHIBITORS | RAD51, MRE11, RAD54L | ESR2 1698/4885ALDH1A1 4493/4885IDO1 2147/4885 |
| US-20190194182-A1 | RAD51 INHIBITORS | RAD51, MRE11, RAD54L | ESR2 1698/4885ALDH1A1 4493/4885IDO1 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.