Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 7/20 | 0.73 |
| ▸ | STAT6 | P42226 | 2/20 | 0.73 |
| ▸ | DPP4 | P27487 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.73 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.73 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.73 |
| ▸ | GAPDH | P04406 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.73 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.73 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.73 |
| ▸ | PI4KA | P42356 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.73 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.73 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.73 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272122 | 1.00 | SLC29A1 (0.73) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL1858029 | 1.00 | SLC29A1 (0.73) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL19443159 | 1.00 | SLC29A1 (0.73) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL319667 | 1.00 | SLC29A1 (0.73) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL278513 | 1.00 | SLC29A1 (0.73) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL67126 | 1.00 | SLC29A1 (0.73) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL10062644 | 1.00 | SLC29A1 (0.73) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL272123 | 1.00 | SLC29A1 (0.73) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL10340725 | 1.00 | SLC29A1 (0.73) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL91050 | 1.00 | SLC29A1 (0.73) | SLC29A1STAT6DPP4MEN1SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3988560-A1 | SMALL-MOLECULE COMPOUND HAVING A2A ADENOSINE RECEPTOR ANTAGONISM | Academy Of Military Medical Sciences (CN) | 2022-04-27 | — | — | EP | disclosed |
| WO-2020253870-A1 | 6-HYDRAZINOADENOSINE COMPOUND HAVING A2A ADENOSINE RECEPTOR AGONIST ACTIVITY | 中国人民解放军军事科学院军事医学研究院 | 2020-12-24 | — | — | WO | disclosed |
| US-10654834-B2 | Non-systemic TGR5 agonists | Venenum Biodesign, LLC (US) | 2020-05-19 | — | — | US | disclosed |
| US-20190330191-A1 | NOVEL NON-SYSTEMIC TGR5 AGONISTS | Venenum Biodesign, LLC (US) | 2019-10-31 | — | — | US | disclosed |
| US-10342818-B2 | Dual-action compounds targeting adenosine A2A receptor and adenosine transporter for prevention and treatment of neurodegenerative diseases | ACADEMIA SINICA (TW) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10342818-B2 | Dual-action compounds targeting adenosine A2A receptor and adenosine transporter for prevention and treatment of neurodegenerative diseases | ADORA2A, ADORA1, ADORA3 | SLC29A1 6/4885STAT6 4641/4885DPP4 1291/4885 |
| US-20190330191-A1 | NOVEL NON-SYSTEMIC TGR5 AGONISTS | GPR119, FFAR1, FFAR3 | SLC29A1 661/4885STAT6 1479/4885DPP4 116/4885 |
| US-10654834-B2 | Non-systemic TGR5 agonists | GPR119, SSTR5, FFAR3 | SLC29A1 642/4885STAT6 1449/4885DPP4 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.