SCHEMBL21140197

SCHEMBL21140197

Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OC3[C@@H](O)[C@@H](COP(=O)(O)O)O[C@H]3n3cnc4c(N)ncnc43)[C@H](O)C2O)c(=O)[nH]1

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RNASEL Q05823 14/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23430015 1.00 RNASEL (0.82) RNASEL
SCHEMBL23430014 1.00 RNASEL (0.82) RNASEL
SCHEMBL23430070 1.00 RNASEL (0.82) RNASEL
SCHEMBL9951563 0.96 RNASEL (0.76) RNASEL
SCHEMBL30084833 0.96 RNASEL (0.76) RNASEL
SCHEMBL1526208 0.96 RNASEL (0.75) RNASEL
SCHEMBL22381534 0.95 RNASEL (0.74) RNASEL
SCHEMBL21943911 0.95 RNASEL (0.74) RNASEL
SCHEMBL22399331 0.95 RNASEL (0.74) RNASEL
SCHEMBL21504456 0.95 RNASEL (0.74) RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10912834-B2 Topical formulations based on ionic species for skin treatment THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-02-09 — — US disclosed
US-20190192661-A1 TOPICAL FORMULATIONS BASED ON IONIC SPECIES FOR SKIN TREATMENT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190192661-A1 TOPICAL FORMULATIONS BASED ON IONIC SPECIES FOR SKIN TREATMENT CUTA, KRT18, SLC38A7 RNASEL 1654/4885
US-10912834-B2 Topical formulations based on ionic species for skin treatment CUTA, KRT18, SLC38A7 RNASEL 1654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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