Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20441975 | 0.80 | ALDH1A1 (0.43) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL17166806 | 0.79 | CYP1A2 (0.47) | KDM4EMAPTALDH1A1TP53HPGD | |
| SCHEMBL22060944 | 0.76 | ALDH1A1 (0.40) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL20735169 | 0.76 | MAPT (0.43) | KDM4EMAPTALDH1A1TP53HPGD | |
| SCHEMBL26456100 | 0.76 | MAPT (0.43) | KDM4EMAPTALDH1A1TP53HPGD | |
| SCHEMBL24216259 | 0.76 | AHR (0.50) | KDM4EMAPTALDH1A1TP53HPGD | |
| SCHEMBL18819919 | 0.76 | MAOB (0.44) | KDM4EMAPTALDH1A1TP53HPGD | |
| SCHEMBL17942703 | 0.76 | KDM4E (0.43) | KDM4EMAPTALDH1A1TP53HPGD | |
| SCHEMBL23783961 | 0.73 | KDM4E (0.41) | KDM4EMAPTALDH1A1TP53HPGD | |
| SCHEMBL1610145 | 0.73 | MAPT (0.50) | KDM4EMAPTALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502107-A1 | 1-AMINODIBENZOFURAN-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | Samsung Display Co., Ltd. (KR) | 2019-06-26 | — | — | EP | disclosed |