SCHEMBL1610145

SCHEMBL1610145

Cc1ccc2oc3ccc(C)cc3c2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.50
HTT P42858 1/20 0.50
ALDH1A1 P00352 6/20 0.48
KDM4E B2RXH2 6/20 0.48
TP53 P04637 3/20 0.48
HPGD P15428 3/20 0.48
HSD17B10 Q99714 3/20 0.48
CYP3A4 P08684 3/20 0.48
NQO1 P15559 1/20 0.48
KCNH2 Q12809 1/20 0.47
MAPK1 P28482 2/20 0.47
ALPG P10696 1/20 0.47
ATM Q13315 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
SMN1; SMN2 Q16637 4/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
CSNK2A2 P19784 1/20 0.46
CSNK2B P67870 1/20 0.46
CSNK2A1 P68400 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19155599 0.95 MAPT (0.47) MAPTHTTALDH1A1KDM4ETP53
SCHEMBL22271444 0.95 MAPT (0.47) MAPTHTTALDH1A1KDM4ETP53
SCHEMBL10141873 0.91 MAOB (0.47) MAPTHTTALDH1A1KDM4ETP53
SCHEMBL10133860 0.91 MAPT (0.50) MAPTHTTALDH1A1KDM4ETP53
SCHEMBL808014 0.89 MAPT (0.59) MAPTALDH1A1KDM4ETP53HPGD
SCHEMBL862490 0.89 MAPT (0.43) MAPTHTTALDH1A1KDM4ETP53
SCHEMBL22738448 0.89 MAOB (0.46) MAPTHTTALDH1A1KDM4ETP53
SCHEMBL12203228 0.89 MAPT (0.49) MAPTHTTALDH1A1KDM4ETP53
SCHEMBL14294841 0.87 CSNK2A2 (0.54) MAPTHTTALDH1A1KDM4EHPGD
SCHEMBL13783172 0.87 MAPT (0.42) MAPTHTTALDH1A1KDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 758 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4013694-A CERIA CATALYZEA CONVERSION OF PHENOLS TO DIBENZOFURANS MONSANTO COMPANY (US) 1977-03-22 US claimed
US-4009185-A Conversion of diphenylethers to dibenzofurans using catalysts containing ceria MONSANTO COMPANY (US) 1977-02-22 US claimed
US-4008254-A Ceria catalyzed conversion of phenols to dibenzofurans in the presence of water vapor MONSANTO COMPANY (US) 1977-02-15 US claimed
US-20240244946-A1 ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244947-A1 ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244947-A1 ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240228713-A1 ANION EXCHANGE POLYMERS AND MEMBRANES FOR ELECTROLYSIS UOP LLC 2024-07-11 US disclosed
US-20240228713-A1 ANION EXCHANGE POLYMERS AND MEMBRANES FOR ELECTROLYSIS UOP LLC 2024-07-11 US disclosed
WO-2024126322-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2024-06-20 WO disclosed
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LIMITED (IE) 2024-01-25 US disclosed
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LIMITED (IE) 2024-01-25 US disclosed
US-20070296047-A1 THIN FILM TRANSISTORS WITH POLY(ARYLENE ETHER) POLYMERS AS GATE DIELECTRICS AND PASSIVATION LAYERS AIR PRODUCTS AND CHEMICALS, INC. (US) 2007-12-27 US disclosed
US-7309833-B2 Photovoltaic devices comprising layer(s) of photoactive organics dissolved in high Tg polymers AIR PRODUCTS AND CHEMICALS, INC. (US) 2007-12-18 US disclosed
US-7309833-B2 Photovoltaic devices comprising layer(s) of photoactive organics dissolved in high Tg polymers AIR PRODUCTS AND CHEMICALS, INC. (US) 2007-12-18 US disclosed
EP-1857521-A1 ORGANIC ELECTRIC FIELD LIGHT EMITTING ELEMENT AND PRODUCTION THEREFOR Mitsubishi Chemical Corporation (JP) 2007-11-21 EP disclosed
EP-1394618-B1 Electrophotographic Photosensitive Member, Process Cartridge and Electrophotographic Apparatus CANON KK (JP) 2007-05-02 EP disclosed
US-4042603-A SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE UBE INDUSTRIES, LTD. (JA) 1977-08-16 US disclosed
US-4013694-A CERIA CATALYZEA CONVERSION OF PHENOLS TO DIBENZOFURANS MONSANTO COMPANY (US) 1977-03-22 US disclosed
US-4009185-A Conversion of diphenylethers to dibenzofurans using catalysts containing ceria MONSANTO COMPANY (US) 1977-02-22 US disclosed
US-4008254-A Ceria catalyzed conversion of phenols to dibenzofurans in the presence of water vapor MONSANTO COMPANY (US) 1977-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240244946-A1 ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS GPX1, PER2, SOD1 MAPT 993/4885HTT 3977/4885ALDH1A1 10/4885
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device TMEM109, SLC39A11, SLC39A14 MAPT 1229/4885HTT 1208/4885ALDH1A1 981/4885
US-20240244947-A1 ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS PER2, GPX1, SOD1 MAPT 899/4885HTT 3883/4885ALDH1A1 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.