Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | ATP4A | P20648 | 19/20 | 0.44 |
| ▸ | ATP4B | P51164 | 19/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21140914 | 0.84 | APP (0.62) | APPATP4AATP4B | |
| SCHEMBL21140950 | 0.81 | ATP4A (0.49) | APPATP4AATP4B | |
| SCHEMBL21141048 | 0.77 | ATP4A (0.47) | APPATP4AATP4B | |
| SCHEMBL21140953 | 0.74 | APP (0.50) | APPATP4AATP4B | |
| SCHEMBL21140910 | 0.72 | ATP4A (0.49) | APPATP4AATP4B | |
| SCHEMBL21140920 | 0.70 | ATP4A (0.47) | APPATP4AATP4B | |
| SCHEMBL21141288 | 0.69 | ATP4A (0.50) | APPATP4AATP4B | |
| SCHEMBL15602913 | 0.67 | APP (0.69) | APP | |
| SCHEMBL10233638 | 0.66 | CYP3A4 (0.61) | — | |
| SCHEMBL21141014 | 0.65 | APP (0.57) | APPATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10335504-B2 | Heterocyclic molecules for biomedical imaging and therapeutic applications | WASHINGTON UNIVERSITY (US) | 2019-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10335504-B2 | Heterocyclic molecules for biomedical imaging and therapeutic applications | APP, PSEN1, BACE1 | APP 1/4885ATP4A 421/4885ATP4B 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.