Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 12/20 | 0.49 |
| ▸ | ATP4B | P51164 | 12/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | INSR | P06213 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21140914 | 0.86 | APP (0.62) | ATP4AATP4BAPP | |
| SCHEMBL21141288 | 0.86 | ATP4A (0.50) | ATP4AATP4BMEN1MAPTKMT2A | |
| SCHEMBL21140953 | 0.83 | APP (0.50) | ATP4AATP4BMEN1MAPTKMT2A | |
| SCHEMBL21140896 | 0.81 | APP (0.45) | ATP4AATP4BAPP | |
| SCHEMBL4017956 | 0.80 | RAB9A (0.54) | ATP4AATP4BMEN1MAPTKMT2A | |
| SCHEMBL4017957 | 0.80 | RAB9A (0.54) | ATP4AATP4BMEN1MAPTKMT2A | |
| SCHEMBL21141048 | 0.78 | ATP4A (0.47) | ATP4AATP4BAPP | |
| SCHEMBL17953950 | 0.77 | APP (0.61) | ATP4AATP4BMEN1MAPTKMT2A | |
| SCHEMBL4012221 | 0.76 | RAB9A (0.49) | ATP4AATP4BMEN1MAPTKMT2A | |
| SCHEMBL21140910 | 0.73 | ATP4A (0.49) | ATP4AATP4BAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10335504-B2 | Heterocyclic molecules for biomedical imaging and therapeutic applications | WASHINGTON UNIVERSITY (US) | 2019-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10335504-B2 | Heterocyclic molecules for biomedical imaging and therapeutic applications | APP, PSEN1, BACE1 | ATP4A 421/4885ATP4B 365/4885MEN1 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.