Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128648 | 0.85 | ALDH1A1 (0.71) | HTTALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL24386414 | 0.85 | HTT (0.58) | HTTALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL21141312 | 0.84 | ALDH1A1 (0.74) | HTTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL21141304 | 0.83 | HPGD (0.69) | HTTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL13767830 | 0.81 | HTT (0.72) | HTTALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL24175872 | 0.81 | HTT (0.72) | HTTALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL16127374 | 0.81 | ALDH1A1 (0.65) | HTTALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL13753184 | 0.80 | HTT (0.53) | HTTALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL21141297 | 0.79 | KDM4E (0.58) | HTTCYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL21141301 | 0.78 | RAB9A (0.56) | HTTALDH1A1MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10646850-B2 | Material for blood purification | TORAY INDUSTRIES, INC. (JP) | 2020-05-12 | — | — | US | disclosed |
| US-20190184371-A1 | MATERIAL FOR BLOOD PURIFICATION | TORAY INDUSTRIES, INC. (JP) | 2019-06-20 | — | — | US | disclosed |