SCHEMBL21141917

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14867055	0.88	MAPT (0.41)	ALDH1A1MAPTPOLBTSHRMAOA
	SCHEMBL24248347	0.85	ALDH1A1 (0.38)	ALDH1A1MAPTMEN1KMT2ANPC1
	SCHEMBL13048615	0.82	ALDH1A1 (0.35)	ALDH1A1MAPTNPC1RAB9APOLB
	SCHEMBL25945207	0.81	ALDH1A1 (0.34)	ALDH1A1MAPTPOLBTSHRLMNA
	SCHEMBL21141921	0.81	ALDH1A1 (0.34)	ALDH1A1MAPTNPC1RAB9APOLB
	SCHEMBL23969913	0.81	ALDH1A1 (0.34)	ALDH1A1MAPTPOLBTSHRMAOA
	Lithium Ion SCHEMBL30085325	0.80	POLB (0.33)	ALDH1A1MAPTNPC1RAB9APOLB
	SCHEMBL23664989	0.78	PPARG (0.33)	ALDH1A1MAPTNPC1RAB9APOLB
	SCHEMBL21367618	0.77	MAPT (0.49)	ALDH1A1MAPTMEN1KMT2ANPC1
	SCHEMBL25712164	0.77	MAPT (0.49)	ALDH1A1MAPTMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.