SCHEMBL23969913

SCHEMBL23969913

C=Cc1ccc(COc2c(F)c(F)c(C(c3c(F)c(F)c(OCc4ccc(C=C)cc4)c(F)c3F)(c3c(F)c(F)c(OCc4ccc(C=C)cc4)c(F)c3F)c3c(F)c(F)c(OCc4ccc(C=C)cc4)c(F)c3F)c(F)c2F)cc1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.34
▸ POLB P06746 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ HIF1A Q16665 1/20 0.32
▸ MAOA P21397 1/20 0.31
▸ MAOB P27338 1/20 0.31
▸ TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14867055 0.89 MAPT (0.41) ALDH1A1POLBMAPTTDP1L3MBTL1
SCHEMBL23664989 0.88 PPARG (0.33) ALDH1A1POLBMAPTTDP1L3MBTL1
SCHEMBL13048615 0.83 ALDH1A1 (0.35) ALDH1A1POLBMAPTTDP1L3MBTL1
SCHEMBL21141921 0.81 ALDH1A1 (0.34) ALDH1A1POLBMAPTTDP1L3MBTL1
SCHEMBL21141917 0.81 ALDH1A1 (0.46) ALDH1A1POLBMAPTTDP1L3MBTL1
Lithium Ion SCHEMBL30085325 0.80 POLB (0.33) ALDH1A1POLBMAPTTDP1L3MBTL1
SCHEMBL2742186 0.77 TDP1 (0.42) ALDH1A1POLBMAPTTDP1L3MBTL1
SCHEMBL8644283 0.73 ALDH1A1 (0.42) ALDH1A1POLBMAPTTDP1L3MBTL1
SCHEMBL14655816 0.71 ALDH1A1 (0.41) ALDH1A1POLBMAPTL3MBTL1HIF1A
SCHEMBL24248347 0.71 ALDH1A1 (0.38) ALDH1A1MAPTL3MBTL1HIF1AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309369-A1 Organic Light-Emitting Device LG CHEM, LTD. (KR) 2023-09-28 — — US disclosed
US-11737300-B2 Coating composition and organic light-emitting device LG CHEM, LTD. (KR) 2023-08-22 — — US disclosed
US-20230043088-A1 Organic Light Emitting Device LG CHEM, LTD. (KR) 2023-02-09 — — US disclosed
US-11165037-B2 Organic light-emitting diode LG CHEM, LTD. 2021-11-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11165037-B2 Organic light-emitting diode L3MBTL3, CRY2, ALDH1A2 ALDH1A1 109/4885POLB 1334/4885MAPT 1281/4885
US-11737300-B2 Coating composition and organic light-emitting device CD59, CLTB, EPCAM ALDH1A1 2135/4885POLB 690/4885MAPT 207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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