SCHEMBL21143149

SCHEMBL21143149

Cc1cc(O)c2c(c1)OC(=O)CC2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 2/20 0.37
HPGD P15428 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
SIRT1 Q96EB6 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ALDH2 P05091 2/20 0.36
ALDH3A1 P30838 1/20 0.36
SELL P14151 1/20 0.35
SELP P16109 1/20 0.35
SELE P16581 1/20 0.35
ACHE P22303 1/20 0.35
TSHR P16473 1/20 0.34
ALDH1A1 P00352 2/20 0.33
PIM1 P11309 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6832823 0.81 ALDH2 (0.41) GLAHPGDKDM4ECYP1A2CYP2C9
SCHEMBL2929767 0.81 ALDH1A1 (0.43) GLAHPGDKDM4ECYP1A2CYP2C9
SCHEMBL30748275 0.81 ALDH1A1 (0.43) GLAHPGDKDM4ECYP1A2CYP2C9
SCHEMBL6838519 0.77 HPGD (0.36) GLAHPGDKDM4ECYP1A2CYP2C9
SCHEMBL21495184 0.76 KDM4E (0.38) GLAHPGDKDM4ECYP1A2CYP2C9
SCHEMBL2935561 0.75 CYP19A1 (0.42) GLAHPGDKDM4ECYP1A2CYP2C9
SCHEMBL21500706 0.74 EGFR (0.38) KDM4EALDH1A1
SCHEMBL5535613 0.72 SELL (0.39) HSD17B10SELLSELPSELEACHE
SCHEMBL8777243 0.70 KDM4E (0.50) GLAHPGDKDM4ECYP1A2CYP2C9
SCHEMBL21495181 0.70 MAOB (0.36) GLAHPGDKDM4ECYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022256480-A1 ARYLCOUMARIN SYNTHESIS WITH AZEOTROPIC REMOVAL OF WATER CONAGEN INC. (US) 2022-12-08 WO disclosed
EP-3245197-B1 COMPOSITIONS AND METHODS FOR MODULATING SWEET TASTE CHROMOCELL CORP (US) 2019-07-03 EP disclosed