Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832823 | 0.81 | ALDH2 (0.41) | ALDH2ALDH3A1MAPTHPGDGLA | |
| SCHEMBL30748275 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1MAPTHPGDGLA | |
| SCHEMBL2929767 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1MAPTHPGDGLA | |
| SCHEMBL6836704 | 0.76 | ALDH2 (0.37) | ALDH2ALDH3A1HPGDGLAKDM4E | |
| SCHEMBL18721194 | 0.76 | PTPN1 (0.40) | KMT2AMEN1HPGDGLAKDM4E | |
| SCHEMBL21143149 | 0.75 | GLA (0.37) | ALDH2ALDH3A1KMT2AMEN1MAPT | |
| SCHEMBL15800840 | 0.75 | KDM4E (0.34) | KMT2AMEN1HPGDGLAKDM4E | |
| SCHEMBL11013926 | 0.72 | KDM4E (0.38) | ALDH2ALDH3A1KMT2AMEN1HPGD | |
| SCHEMBL30067255 | 0.72 | PBRM1 (0.46) | KMT2AMEN1MAPTTHRBHPGD | |
| SCHEMBL5547659 | 0.72 | MAOA (0.41) | CYP19A1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256480-A1 | ARYLCOUMARIN SYNTHESIS WITH AZEOTROPIC REMOVAL OF WATER | CONAGEN INC. (US) | 2022-12-08 | — | — | WO | disclosed |
| US-20100291009-A1 | PREPARATION COMPRISING CHROMAN-2-ONE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20100291009-A1 | PREPARATION COMPRISING CHROMAN-2-ONE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20100291009-A1 | PREPARATION COMPRISING CHROMAN-2-ONE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-11-18 | — | — | US | disclosed |
| EP-2229169-A1 | PREPARATION CONTAINING CHROMANE-2-ONE DERIVATIVES | Merck Patent GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009089880-A1 | PREPARATION CONTAINING CHROMANE-2-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-07-23 | — | — | WO | disclosed |
| WO-2009089880-A1 | PREPARATION CONTAINING CHROMANE-2-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-07-23 | — | — | WO | disclosed |
| US-4542150-A | INSECTICIDES | CORNELL RESEARCH FOUNDATION, INC. (US) | 1985-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100291009-A1 | PREPARATION COMPRISING CHROMAN-2-ONE DERIVATIVES | RCC1, RB1, RCC2 | CYP19A1 316/4885ALDH2 3443/4885ALDH3A1 2010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.