Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780498 | 0.90 | HTT (0.47) | CYP11B1CYP11B2IDO1GSK3AGSK3B | |
| SCHEMBL23130914 | 0.79 | CYP11B1 (0.63) | CYP11B1CYP11B2IDO1 | |
| SCHEMBL1951380 | 0.79 | CYP11B1 (0.66) | SIGMAR1CYP11B1CYP11B2IDO1TSHR | |
| SCHEMBL6928442 | 0.78 | CYP11B1 (0.56) | SIGMAR1CYP11B1CYP11B2IDO1TSHR | |
| SCHEMBL8862697 | 0.76 | CYP11B1 (0.51) | SIGMAR1CYP11B1CYP11B2IDO1TSHR | |
| SCHEMBL7509773 | 0.76 | CYP11B1 (0.46) | SIGMAR1CYP11B1CYP11B2IDO1TSHR | |
| Hydrochloric Acid SCHEMBL6924270 | 0.76 | CYP11B1 (0.51) | SIGMAR1CYP11B1CYP11B2IDO1TSHR | |
| SCHEMBL409874 | 0.74 | HMOX1 (0.51) | CYP11B1CYP11B2 | |
| SCHEMBL16719005 | 0.73 | CYP11B1 (0.46) | CYP11B1CYP11B2 | |
| SCHEMBL13470151 | 0.71 | CYP11B1 (0.49) | SIGMAR1CYP11B1CYP11B2GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190218188-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190218188-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLE DERIVATIVES | IRF3, MYB, IPMK | SIGMAR1 4246/4885CYP11B1 3162/4885CYP11B2 3491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.