Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA1 | Q13131 | 7/20 | 0.66 |
| ▸ | PRKAA2 | P54646 | 6/20 | 0.66 |
| ▸ | KDR | P35968 | 9/20 | 0.65 |
| ▸ | TLK2 | Q86UE8 | 3/20 | 0.65 |
| ▸ | PDGFRB | P09619 | 11/20 | 0.64 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.63 |
| ▸ | PLK4 | O00444 | 2/20 | 0.62 |
| ▸ | DCLK1 | O15075 | 2/20 | 0.62 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13755270 | 0.95 | PRKAA1 (0.72) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| Trifluoroacetic Acid SCHEMBL2115583 | 0.92 | PDGFRB (0.61) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| SCHEMBL13755273 | 0.86 | KDR (0.68) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| SCHEMBL13755271 | 0.86 | KDR (0.68) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| SCHEMBL13755272 | 0.86 | KDR (0.68) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| Trifluoroacetic Acid SCHEMBL29281305 | 0.85 | PRKAA1 (0.90) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| Hydrochloric Acid SCHEMBL31672473 | 0.85 | KDR (0.67) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| Hydrochloric Acid SCHEMBL2115104 | 0.85 | KDR (0.67) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| SCHEMBL13762214 | 0.84 | KDR (0.69) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| SCHEMBL4018724 | 0.81 | PDGFRB (0.83) | PRKAA1PRKAA2KDRTLK2PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094998-A1 | Oligomer-Protein Tyrosine Kinase Inhibitor Conjugates | NEKTAR THERAPEUTICS (US) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094998-A1 | Oligomer-Protein Tyrosine Kinase Inhibitor Conjugates | PTK2B, ERBB2, FRK | PRKAA1 881/4885PRKAA2 917/4885KDR 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.