Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | FADS1 | O60427 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21146679 | 0.90 | MAOB (0.40) | MAOBTHRBPOLBLMNACYP1A2 | |
| SCHEMBL29390125 | 0.86 | HTT (0.39) | MAOBTHRBKDRPOLBLMNA | |
| SCHEMBL21146220 | 0.86 | HTT (0.39) | MAOBTHRBKDRPOLBLMNA | |
| SCHEMBL23456609 | 0.85 | RAB9A (0.41) | MAOBTHRBPOLBLMNAALDH1A1 | |
| SCHEMBL21146494 | 0.83 | SLC10A1 (0.38) | MAOBTHRBKDRPOLBCYP1A2 | |
| SCHEMBL29390789 | 0.83 | POLB (0.36) | MAOBTHRBKDRPOLBLMNA | |
| SCHEMBL21146208 | 0.83 | POLB (0.36) | MAOBTHRBKDRPOLBLMNA | |
| SCHEMBL29390180 | 0.83 | SLC10A1 (0.38) | MAOBTHRBKDRPOLBCYP1A2 | |
| SCHEMBL21062235 | 0.81 | ALDH1A1 (0.35) | MAOBTHRBPOLBLMNACYP1A2 | |
| SCHEMBL21062236 | 0.81 | ALDH1A1 (0.35) | MAOBTHRBPOLBLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118358-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | VenatoRx Pharmaceuticals, Inc. (US) | 2019-06-20 | — | — | WO | disclosed |