SCHEMBL21147159

SCHEMBL21147159

c1ccc(-c2nc(-c3cccc(-n4c5ccccc5c5ccccc54)c3)nc(-c3ccc(-c4ccccc4)c(-n4c5ccccc5c5ccccc54)c3)n2)cc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
ATM Q13315 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KMT2A Q03164 5/20 0.36
MEN1 O00255 4/20 0.36
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
ABCG2 Q9UNQ0 4/20 0.35
GAA P10253 1/20 0.35
LMNA P02545 1/20 0.35
GLA P06280 1/20 0.35
PDE10A Q9Y233 1/20 0.34
ACP1 P24666 2/20 0.34
IL1R1 P14778 1/20 0.33
PLA2G10 O15496 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21147810 0.99 KDM4E (0.44) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL21147262 0.99 KDM4E (0.46) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL21147809 0.97 ATM (0.42) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL21147848 0.97 KDM4E (0.42) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL21147326 0.97 ATM (0.42) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL26363843 0.97 KDM4E (0.45) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL21147339 0.96 KDM4E (0.41) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL21147269 0.96 KDM4E (0.41) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL21147838 0.96 KDM4E (0.41) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL21147273 0.96 KDM4E (0.41) KDM4EATML3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11706977-B2 Heterocyclic compound, composition including the same, and organic light-emitting device including the heterocyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-11706977-B2 Heterocyclic compound, composition including the same, and organic light-emitting device including the heterocyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-11697645-B2 Heterocyclic compound, composition including heterocyclic compound, and organic light-emitting device including heterocyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-11 US disclosed
US-11697645-B2 Heterocyclic compound, composition including heterocyclic compound, and organic light-emitting device including heterocyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-11 US disclosed
US-20230140682-A1 Heterocyclic compound, composition including the same, and organic light-emitting device including the heterocyclic compound SAMSUNG ELECTRONICS CO LTD (KR) 2023-05-04 US disclosed
US-20230140682-A1 Heterocyclic compound, composition including the same, and organic light-emitting device including the heterocyclic compound SAMSUNG ELECTRONICS CO LTD (KR) 2023-05-04 US disclosed
US-11542252-B2 Heterocyclic compound, composition including the same, and organic light-emitting device including the heterocyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-01-03 US disclosed
US-20210184132-A1 COMPOUND, COMPOSITION INCLUDING THE SAME, LIQUID COMPOSITION, AND ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-06-17 US disclosed
US-20200212314-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-07-02 US disclosed
US-20200207732-A1 HETEROCYCLIC COMPOUND, COMPOSITION INCLUDING HETEROCYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-07-02 US disclosed
US-20200212307-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-07-02 US disclosed
US-20200207739-A1 Heterocyclic compound, composition including the same, and organic light-emitting device including the heterocyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-07-02 US disclosed
EP-3675194-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2020-07-01 EP disclosed
US-20190214570-A1 HETEROCYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11697645-B2 Heterocyclic compound, composition including heterocyclic compound, and organic light-emitting device including heterocyclic compound CYP1B1, CYP1A1, CCNT1 KDM4E 4155/4885ATM 1467/4885L3MBTL1 517/4885
US-11542252-B2 Heterocyclic compound, composition including the same, and organic light-emitting device including the heterocyclic compound CCNT1, CCNA1, CYP1B1 KDM4E 3931/4885ATM 1887/4885L3MBTL1 175/4885
US-11706977-B2 Heterocyclic compound, composition including the same, and organic light-emitting device including the heterocyclic compound CRY1, CYP1B1, CYP1A1 KDM4E 2739/4885ATM 2932/4885L3MBTL1 1990/4885
US-20210184132-A1 COMPOUND, COMPOSITION INCLUDING THE SAME, LIQUID COMPOSITION, AND ORGANIC ELECTROLUMINESCENT DEVICE TERT, TELO2, POT1 KDM4E 1003/4885ATM 1487/4885L3MBTL1 33/4885
US-20200207732-A1 HETEROCYCLIC COMPOUND, COMPOSITION INCLUDING HETEROCYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND CYP1B1, CYP1A1, CCNT1 KDM4E 4155/4885ATM 1467/4885L3MBTL1 517/4885
US-20230140682-A1 Heterocyclic compound, composition including the same, and organic light-emitting device including the heterocyclic compound CCNT1, CCNA1, CYP1B1 KDM4E 3931/4885ATM 1887/4885L3MBTL1 175/4885
US-20190214570-A1 HETEROCYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND CRY1, CYP1B1, CYP1A1 KDM4E 2739/4885ATM 2932/4885L3MBTL1 1990/4885
US-20200212307-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND CCNB1, CCNA1, CCNT1 KDM4E 4280/4885ATM 827/4885L3MBTL1 285/4885
US-20200207739-A1 Heterocyclic compound, composition including the same, and organic light-emitting device including the heterocyclic compound CCNT1, CCNA1, CYP1B1 KDM4E 3931/4885ATM 1887/4885L3MBTL1 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.