Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15443585 | 0.88 | POLB (0.45) | POLBCA12CA1CA2CA9 | |
| SCHEMBL15462786 | 0.88 | POLB (0.43) | POLBCA12CA1CA2CA9 | |
| SCHEMBL18648292 | 0.85 | POLB (0.41) | POLBCA12CA1CA2CA9 | |
| SCHEMBL862788 | 0.82 | CA12 (0.45) | POLBCA12CA1CA2CA9 | |
| SCHEMBL21147736 | 0.82 | CA12 (0.45) | POLBCA12CA1CA2CA9 | |
| SCHEMBL17878210 | 0.81 | MGLL (0.49) | POLBCA12CA1CA2CA9 | |
| SCHEMBL13695372 | 0.78 | CA12 (0.41) | POLBCA12CA1CA2CA9 | |
| SCHEMBL13553156 | 0.75 | GAA (0.37) | POLBCA12CA1CA9MAPT | |
| SCHEMBL12812236 | 0.75 | NPC1 (0.43) | POLBCA12CA1CA2CA9 | |
| SCHEMBL15457961 | 0.74 | SMN1; SMN2 (0.43) | POLBCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2692796-B1 | COMPOSITION | SUMITOMO CHEMICAL CO (JP) | 2019-07-10 | — | — | EP | disclosed |