Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10014682 | 0.87 | CA12 (0.55) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL15457961 | 0.84 | SMN1; SMN2 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL15443110 | 0.84 | SMN1; SMN2 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL21147735 | 0.82 | POLB (0.44) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL862493 | 0.80 | CA12 (0.49) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL13553156 | 0.79 | GAA (0.37) | CA12CA1CA9ALDH1A1LMNA | |
| SCHEMBL18561315 | 0.79 | CA12 (0.51) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL22837832 | 0.77 | NR1H4 (0.39) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL18823083 | 0.77 | MAPT (0.41) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL23876300 | 0.77 | ALDH1A1 (0.51) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2692796-B1 | COMPOSITION | SUMITOMO CHEMICAL CO (JP) | 2019-07-10 | — | — | EP | disclosed |