Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13376542 | 0.77 | CYP2C9 (0.57) | CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL13816219 | 0.76 | ALDH1A1 (0.38) | CYP2C9CYP3A4CYP2D6CA12CA2 | |
| SCHEMBL14473226 | 0.76 | CA12 (0.39) | CYP2C9CA12CA2CA9 | |
| SCHEMBL23829636 | 0.75 | MAPT (0.48) | CYP2C9CYP3A4CYP2D6CA12CA2 | |
| SCHEMBL23829633 | 0.75 | MAPT (0.48) | CYP2C9CYP3A4CYP2D6CA12CA2 | |
| SCHEMBL21010629 | 0.75 | CYP2C9 (0.45) | CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL24289374 | 0.75 | NPC1 (0.48) | CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL14273549 | 0.74 | NPC1 (0.38) | — | |
| SCHEMBL12000938 | 0.72 | CYP2C9 (0.39) | CYP2C9CYP3A4CYP2D6CA12CA2 | |
| SCHEMBL10763347 | 0.72 | CASP3 (0.44) | CYP2C9CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683256-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2020-06-16 | — | — | US | disclosed |
| US-20190210954-A1 | Process for Preparing Substituted Biphenyls | LIANHE CHEMICAL TECHNOLOGY CO., LTD (CN) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683256-B2 | Process for preparing substituted biphenyls | PIK3CA, PIK3CB, PIK3CG | CYP2C9 366/4885CYP3A4 72/4885CYP2D6 335/4885 |
| US-20190210954-A1 | Process for Preparing Substituted Biphenyls | PIK3CA, PIK3CB, PIK3CG | CYP2C9 366/4885CYP3A4 72/4885CYP2D6 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.