SCHEMBL21148748

SCHEMBL21148748

c1ccc(-c2ccc(-c3nc(-c4cccc(-c5cccc6oc7ccccc7c56)c4)nc(-c4cccc5oc6ccccc6c45)n3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.40
PLA2G4A P47712 4/20 0.40
ALOX5 P09917 1/20 0.39
MAPT P10636 5/20 0.38
ALDH1A1 P00352 5/20 0.38
HPGD P15428 4/20 0.38
TSHR P16473 3/20 0.38
KDM4E B2RXH2 3/20 0.38
ATM Q13315 2/20 0.38
TP53 P04637 1/20 0.38
NFKB1 P19838 1/20 0.38
MAPK1 P28482 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PLA2G10 O15496 1/20 0.37
BACE1 P56817 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21109244 0.97 PLA2G2A (0.41) PLA2G2APLA2G4AALOX5MAPTALDH1A1
SCHEMBL23385393 0.97 MAPT (0.40) PLA2G2APLA2G4AALOX5MAPTALDH1A1
SCHEMBL21109245 0.97 PLA2G2A (0.41) PLA2G2APLA2G4AALOX5MAPTALDH1A1
SCHEMBL23822703 0.97 PLA2G2A (0.41) PLA2G2APLA2G4AALOX5MAPTALDH1A1
SCHEMBL21425214 0.96 PLA2G2A (0.39) PLA2G2APLA2G4AALOX5MAPTALDH1A1
SCHEMBL23821000 0.96 PLA2G2A (0.40) PLA2G2APLA2G4AALOX5MAPTALDH1A1
SCHEMBL24657303 0.96 PLA2G2A (0.43) PLA2G2APLA2G4AALOX5MAPTALDH1A1
SCHEMBL21108849 0.96 PLA2G2A (0.43) PLA2G2APLA2G4AALOX5MAPTALDH1A1
SCHEMBL24657873 0.96 PLA2G2A (0.43) PLA2G2APLA2G4AALOX5MAPTALDH1A1
SCHEMBL21147392 0.96 PLA2G2A (0.43) PLA2G2APLA2G4AALOX5MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20230165145-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-05-25 US disclosed
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 PLA2G2A 1762/4885PLA2G4A 1920/4885ALOX5 306/4885
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 PLA2G2A 1762/4885PLA2G4A 1920/4885ALOX5 306/4885
US-20230165145-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT EMITTING DEVICE CRY1, CYP1A1, CYP1B1 PLA2G2A 3909/4885PLA2G4A 3952/4885ALOX5 519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.