SCHEMBL21150803

SCHEMBL21150803

NC1CC2(C1)NC(=O)N(Cc1ccccc1)C2=O

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.64
▸ CYP2C19 P33261 2/20 0.50
▸ CNR1 P21554 1/20 0.49
▸ ALDH1A1 P00352 4/20 0.47
▸ ELANE P08246 3/20 0.46
▸ MEN1 O00255 2/20 0.45
▸ CYP19A1 P11511 2/20 0.45
▸ F2 P00734 1/20 0.44
▸ PLG P00747 1/20 0.44
▸ CTSG P08311 1/20 0.44
▸ CMA1 P23946 1/20 0.44
▸ CTRC Q99895 1/20 0.44
▸ GSK3A P49840 1/20 0.44
▸ GSK3B P49841 1/20 0.44
▸ SMN1; SMN2 Q16637 4/20 0.44
▸ LMNA P02545 1/20 0.44
▸ MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5317587 0.85 KMT2A (0.69) KMT2ACYP2C19CNR1ALDH1A1MEN1
SCHEMBL13879509 0.80 KMT2A (0.91) KMT2ACYP2C19ALDH1A1MEN1SMN1; SMN2
SCHEMBL3249503 0.77 KMT2A (0.75) KMT2ACYP2C19CNR1ALDH1A1ELANE
SCHEMBL25000449 0.76 KMT2A (0.53) KMT2ACYP2C19CNR1ALDH1A1ELANE
SCHEMBL3233520 0.76 KMT2A (0.73) KMT2ACYP2C19CNR1ALDH1A1ELANE
Hydrochloric Acid SCHEMBL23610493 0.76 KMT2A (0.73) KMT2ACYP2C19CNR1ALDH1A1ELANE
SCHEMBL30180963 0.75 KMT2A (0.56) KMT2ACYP2C19CNR1ALDH1A1ELANE
SCHEMBL2907609 0.75 KMT2A (0.62) KMT2ACYP2C19CNR1ALDH1A1ELANE
SCHEMBL9965983 0.75 KMT2A (0.71) KMT2ACYP2C19CNR1ALDH1A1ELANE
SCHEMBL11492041 0.74 KMT2A (0.61) KMT2ACYP2C19CNR1ALDH1A1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572370-B2 CD16A binding agents and uses thereof BIOHAVEN THERAPEUTICS LTD. (US) 2023-02-07 — — US disclosed
WO-2019136442-A1 CD16A BINDING AGENTS AND USES THEREOF KLEO PHARMACEUTICALS, INC. (US) 2019-07-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572370-B2 CD16A binding agents and uses thereof FCGR1A, FCGR2A, FCGR3B KMT2A 499/4885CYP2C19 3692/4885CNR1 813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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