Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21371646 | 0.83 | POLB (0.40) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL21150668 | 0.80 | TSHR (0.36) | LMNAHTTMAPTMEN1KMT2A | |
| SCHEMBL21371642 | 0.79 | POLB (0.46) | LMNASMN1; SMN2MAPTKMT2AL3MBTL1 | |
| SCHEMBL8363999 | 0.79 | POLB (0.50) | LMNASMN1; SMN2MAPTKMT2AL3MBTL1 | |
| SCHEMBL8363998 | 0.78 | POLB (0.53) | LMNASMN1; SMN2MAPTKMT2AL3MBTL1 | |
| SCHEMBL1509522 | 0.76 | IDO1 (0.36) | LMNAFPR2KMT2A | |
| SCHEMBL7394414 | 0.76 | NEK2 (0.44) | L3MBTL1KDM4E | |
| SCHEMBL8363733 | 0.74 | IDO1 (0.39) | LMNAHTTKMT2AL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL21753306 | 0.74 | IDO1 (0.36) | LMNAFPR2KMT2A | |
| SCHEMBL15331142 | 0.74 | THRB (0.51) | LMNAHTTSMN1; SMN2THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |