Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21150993 | 0.80 | LMNA (0.50) | LMNAMAPTHTTMEN1KMT2A | |
| SCHEMBL10204552 | 0.79 | SIGMAR1 (0.36) | TSHRCYP2C19IDO1TDO2 | |
| SCHEMBL21371646 | 0.78 | POLB (0.40) | TSHRCYP2C19LMNAIDO1TDO2 | |
| SCHEMBL24974722 | 0.75 | BACE1 (0.38) | CRBNLMNAMAPTCYP19A1 | |
| SCHEMBL21371642 | 0.74 | POLB (0.46) | TSHRCYP2C19LMNAIDO1TDO2 | |
| SCHEMBL24127455 | 0.74 | TSHR (0.38) | TSHRCYP2C19CRBNLMNAIDO1 | |
| SCHEMBL21371635 | 0.74 | TSHR (0.38) | TSHRCYP2C19CRBNLMNAIDO1 | |
| SCHEMBL8363999 | 0.74 | POLB (0.50) | LMNAMAPTKMT2A | |
| SCHEMBL8363998 | 0.72 | POLB (0.53) | LMNAMAPTKMT2A | |
| SCHEMBL19833566 | 0.72 | TSHR (0.37) | TSHRCYP2C19LMNAIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |