Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | PLEC | Q15149 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | CDC25C | P30307 | 1/20 | 0.50 |
| ▸ | GNG2 | P59768 | 1/20 | 0.50 |
| ▸ | GNB1 | P62873 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775968 | 0.82 | USP2 (0.63) | KMT2AUSP2MEN1POLBATM | |
| SCHEMBL12679617 | 0.79 | KMT2A (0.59) | KMT2AUSP2MEN1POLBATM | |
| SCHEMBL13320808 | 0.79 | KMT2A (0.59) | KMT2AUSP2MEN1POLBATM | |
| SCHEMBL12909301 | 0.78 | USP2 (0.68) | KMT2AUSP2MEN1POLBATM | |
| SCHEMBL8427558 | 0.77 | USP2 (0.64) | KMT2AUSP2MEN1POLBATM | |
| SCHEMBL12060569 | 0.76 | USP2 (0.72) | KMT2AUSP2MEN1POLBATM | |
| SCHEMBL23861287 | 0.76 | USP2 (0.59) | KMT2AUSP2MEN1POLBATM | |
| SCHEMBL10762560 | 0.76 | KMT2A (0.59) | KMT2AUSP2MEN1POLBATM | |
| SCHEMBL16019277 | 0.76 | USP2 (0.59) | KMT2AUSP2MEN1POLBATM | |
| SCHEMBL14044262 | 0.76 | USP2 (0.77) | KMT2AUSP2MEN1POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |