Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 6/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565683 | 0.79 | MAPT (0.39) | CYP1A1CYP1A2CYP1B1EGFRMEN1 | |
| SCHEMBL8568767 | 0.78 | HDAC6 (0.45) | CHKAMEN1KMT2AHTTPTGS1 | |
| SCHEMBL7155151 | 0.76 | MEN1 (0.46) | CHKAEGFRSRCMEN1KMT2A | |
| SCHEMBL28620170 | 0.75 | HSP90AA1 (0.54) | MEN1KMT2AHTTHDAC6 | |
| SCHEMBL30129611 | 0.75 | HSP90AA1 (0.54) | MEN1KMT2AHTTHDAC6 | |
| SCHEMBL6364807 | 0.71 | CYP1A2 (0.46) | CYP1A1CYP1A2CYP1B1MEN1KMT2A | |
| SCHEMBL10802759 | 0.70 | CHKA (0.42) | CHKAEGFRMEN1KMT2AHTT | |
| SCHEMBL2198610 | 0.69 | TSHR (0.41) | CHKAEGFRSRCMEN1KMT2A | |
| SCHEMBL10112125 | 0.69 | MEN1 (0.39) | CHKACYP1A2EGFRSRCMEN1 | |
| SCHEMBL20384981 | 0.69 | TSHR (0.41) | CHKAEGFRSRCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |