Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.54 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30129611 | 1.00 | HSP90AA1 (0.54) | HSP90AA1NTSR1VCPHDAC6APP | |
| SCHEMBL28622467 | 0.86 | HSP90AA1 (0.58) | HSP90AA1NTSR1VCPAPPNPSR1 | |
| SCHEMBL28629021 | 0.85 | ACHE (0.40) | HSP90AA1NTSR1VCPHDAC6ALDH1A1 | |
| SCHEMBL30129740 | 0.85 | ACHE (0.40) | HSP90AA1NTSR1VCPHDAC6ALDH1A1 | |
| SCHEMBL30129686 | 0.81 | DAO (0.38) | HSP90AA1NTSR1ALDH1A1MAPTRAB9A | |
| SCHEMBL28636573 | 0.81 | DAO (0.38) | HSP90AA1NTSR1ALDH1A1MAPTRAB9A | |
| SCHEMBL30129485 | 0.79 | TRPM8 (0.43) | HDAC6ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL28617260 | 0.79 | TRPM8 (0.43) | HDAC6ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL21151763 | 0.75 | CHKA (0.36) | HDAC6HTTKMT2AMEN1 | |
| SCHEMBL27167218 | 0.74 | HSP90AA1 (0.64) | HSP90AA1NTSR1VCPNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248420-B | Preparation method of 2-acyl-3-ester group indole derivatives | 西北农林科技大学 | 2023-01-17 | — | — | CN | claimed |
| CN-113248420-A | Preparation method of 2-acyl-3-ester group indole derivatives | 西北农林科技大学 | 2021-08-13 | — | — | CN | claimed |
| CN-113248420-B | Preparation method of 2-acyl-3-ester group indole derivatives | 西北农林科技大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-113248420-A | Preparation method of 2-acyl-3-ester group indole derivatives | 西北农林科技大学 | 2021-08-13 | — | — | CN | disclosed |