Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PARG | Q86W56 | 1/20 | 0.43 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25767750 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HTTGAACYP2C19ATM | |
| SCHEMBL5812323 | 0.80 | PARG (0.62) | ALDH1A1CYP2C19ATMNPSR1KDM4E | |
| SCHEMBL6903823 | 0.78 | NR3C2 (0.53) | ALDH1A1HTTGAACYP2C19NR3C2 | |
| SCHEMBL8707463 | 0.76 | CYP2C19 (0.48) | ALDH1A1HTTGAACYP2C19NR3C2 | |
| SCHEMBL349527 | 0.75 | MAPT (0.66) | ALDH1A1HTTCYP2C19NR3C2ATM | |
| SCHEMBL21078160 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HTTGAACYP2C19ATM | |
| SCHEMBL20254153 | 0.74 | ALDH1A1 (0.55) | ALDH1A1HTTCYP2C19ATMNPSR1 | |
| SCHEMBL24282439 | 0.73 | CYP2C19 (0.45) | ALDH1A1HTTGAACYP2C19ATM | |
| SCHEMBL28404277 | 0.72 | CYP2C19 (0.51) | ALDH1A1HTTGAACYP2C19NR3C2 | |
| SCHEMBL11032086 | 0.71 | ALDH1A1 (0.56) | ALDH1A1HTTGAACYP2C19ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3380591-B1 | SEAL SWELL AGENTS FOR LUBRICATING COMPOSITIONS | LUBRIZOL CORP (US) | 2019-07-10 | — | — | EP | disclosed |