⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25000078 | 0.80 | — | — | |
| SCHEMBL26224054 | 0.66 | ALDH1A1 (0.43) | — | |
| SCHEMBL19084110 | 0.64 | — | — | |
| SCHEMBL23736761 | 0.62 | — | — | |
| SCHEMBL18723239 | 0.62 | — | — | |
| SCHEMBL13670068 | 0.61 | MAPT (0.30) | — | |
| SCHEMBL25729637 | 0.61 | — | — | |
| SCHEMBL22549266 | 0.61 | — | — | |
| SCHEMBL26465501 | 0.61 | — | — | |
| SCHEMBL23879741 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254705-B2 | Cyclic peptide analogs and conjugates thereof | SIRENAS LLC (US) | 2022-02-22 | — | — | US | disclosed |
| US-20190211060-A1 | CYCLIC PEPTIDE ANALOGS AND CONJUGATES THEREOF | SIRENAS LLC (US) | 2019-07-11 | — | — | US | disclosed |