⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712733 | 0.71 | — | — | |
| SCHEMBL14396714 | 0.70 | TP53 (0.30) | — | |
| SCHEMBL26224054 | 0.69 | ALDH1A1 (0.43) | — | |
| SCHEMBL24829552 | 0.68 | — | — | |
| SCHEMBL26137516 | 0.68 | TP53 (0.37) | — | |
| SCHEMBL11509107 | 0.67 | TP53 (0.47) | — | |
| SCHEMBL24235696 | 0.67 | — | — | |
| SCHEMBL24236949 | 0.65 | TSHR (0.42) | — | |
| SCHEMBL21151900 | 0.64 | — | — | |
| SCHEMBL23736761 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10189912-B2 | Carrier immunoglobulins | AMGEN INC. (US) | 2019-01-29 | — | — | US | disclosed |
| US-20170190793-A1 | CARRIER IMMUNOGLOBULINS | AMGEN INC. (US) | 2017-07-06 | — | — | US | disclosed |