Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 5/20 | 0.46 |
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.46 |
| ▸ | UCHL5 | Q9Y5K5 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16263152 | 0.81 | TEK (0.54) | TEKKDREPHB4UCHL5PRMT5 | |
| SCHEMBL16264699 | 0.75 | TEK (0.57) | TEKKDREPHB4UCHL5PRMT5 | |
| SCHEMBL30722374 | 0.75 | TEK (0.57) | TEKKDREPHB4UCHL5PRMT5 | |
| SCHEMBL14987759 | 0.72 | TEK (0.55) | TEKKDREPHB4UCHL5PRMT5 | |
| SCHEMBL28311174 | 0.72 | TEK (0.55) | TEKKDREPHB4UCHL5PRMT5 | |
| SCHEMBL18625808 | 0.71 | PRMT5 (0.55) | TEKKDREPHB4UCHL5PRMT5 | |
| SCHEMBL21573104 | 0.70 | GGPS1 (0.33) | GGPS1 | |
| SCHEMBL16775813 | 0.70 | UCHL5 (0.44) | TEKKDREPHB4UCHL5PRMT5 | |
| SCHEMBL28055960 | 0.70 | UCHL5 (0.44) | TEKKDREPHB4UCHL5PRMT5 | |
| SCHEMBL28593627 | 0.69 | CYP19A1 (0.72) | TEKKDREPHB4UCHL5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |