Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 5/20 | 0.57 |
| ▸ | KDR | P35968 | 4/20 | 0.57 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.54 |
| ▸ | UCHL5 | Q9Y5K5 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.44 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MECP2 | P51608 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16264699 | 1.00 | TEK (0.57) | TEKKDREPHB4UCHL5PRMT5 | |
| SCHEMBL14987759 | 0.88 | TEK (0.55) | TEKKDREPHB4UCHL5PRMT5 | |
| SCHEMBL16263152 | 0.84 | TEK (0.54) | TEKKDREPHB4UCHL5PRMT5 | |
| SCHEMBL18625808 | 0.84 | PRMT5 (0.55) | TEKKDREPHB4UCHL5PRMT5 | |
| SCHEMBL22868173 | 0.83 | KDR (0.59) | TEKKDREPHB4CYP19A1NPC1 | |
| SCHEMBL28311174 | 0.81 | TEK (0.55) | TEKKDREPHB4UCHL5PRMT5 | |
| SCHEMBL22868183 | 0.81 | ROCK2 (0.47) | TEKKDREPHB4CYP19A1NPC1 | |
| SCHEMBL19535294 | 0.81 | KDR (0.57) | TEKKDREPHB4CYP19A1NPC1 | |
| SCHEMBL18760619 | 0.81 | ALOX5 (0.56) | TEKKDREPHB4CYP19A1NPC1 | |
| SCHEMBL28593627 | 0.81 | CYP19A1 (0.72) | TEKKDREPHB4UCHL5CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355512-A | Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment or amelioration of cancer | 托雷莫治疗股份公司 | 2024-01-05 | — | — | CN | disclosed |