Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15763745 | 0.66 | PNMT (0.35) | PNMT | |
| SCHEMBL18612880 | 0.66 | PNMT (0.35) | PNMT | |
| SCHEMBL12711531 | 0.60 | PNMT (0.32) | PNMT | |
| SCHEMBL23177730 | 0.59 | CDK1 (0.39) | — | |
| SCHEMBL23462404 | 0.56 | MAOA (0.35) | — | |
| SCHEMBL12665934 | 0.56 | PNMT (0.47) | PNMT | |
| SCHEMBL19704634 | 0.55 | SNCA (0.42) | — | |
| SCHEMBL23142306 | 0.54 | PNMT (0.45) | PNMT | |
| SCHEMBL23142209 | 0.54 | PNMT (0.49) | PNMT | |
| SCHEMBL19621755 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020046975-A1 | METHODS OF TREATING NEURODEGENERATIVE DISEASES | Seal Rock Therapeutics, Inc. (US) | 2020-03-05 | — | — | WO | disclosed |
| WO-2019136025-A1 | ASK1 INHIBITOR COMPOUNDS AND USES THEREOF | Seal Rock Therapeutics, Inc. (US) | 2019-07-11 | — | — | WO | disclosed |