SCHEMBL21152598

SCHEMBL21152598

CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@]2(C(=O)COC(=O)CCC(=O)O)O1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 10/20 0.77
▸ PGR P06401 6/20 0.77
▸ HIF1A Q16665 4/20 0.77
▸ CYP3A4 P08684 3/20 0.77
▸ LMNA P02545 3/20 0.77
▸ ABCC3 O15438 1/20 0.77
▸ ABCC4 O15439 1/20 0.77
▸ ABCB11 O95342 1/20 0.77
▸ IL5 P05113 1/20 0.77
▸ NR3C2 P08235 1/20 0.77
▸ AR P10275 1/20 0.77
▸ CHRM1 P11229 1/20 0.77
▸ MMP9 P14780 1/20 0.77
▸ NFKB1 P19838 1/20 0.77
▸ THPO P40225 1/20 0.77
▸ SMN1; SMN2 Q16637 1/20 0.77
▸ HSD17B10 Q99714 1/20 0.77
▸ BLM P54132 1/20 0.77
▸ PMP22 Q01453 1/20 0.77
▸ NPSR1 Q6W5P4 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14965919 1.00 NR3C1 (0.77) NR3C1PGRHIF1ACYP3A4LMNA
SCHEMBL21153523 1.00 NR3C1 (0.77) NR3C1PGRHIF1ACYP3A4LMNA
SCHEMBL21153755 1.00 NR3C1 (0.77) NR3C1PGRHIF1ACYP3A4LMNA
SCHEMBL30987798 0.94 NR3C1 (0.77) NR3C1PGRHIF1ACYP3A4LMNA
SCHEMBL5396842 0.93 NR3C1 (0.81) NR3C1PGRHIF1ACYP3A4LMNA
SCHEMBL19583464 0.93 NR3C1 (0.76) NR3C1PGRHIF1ACYP3A4LMNA
SCHEMBL3305265 0.93 NR3C1 (0.76) NR3C1PGRHIF1ACYP3A4LMNA
SCHEMBL18051174 0.93 NR3C1 (0.76) NR3C1PGRHIF1ACYP3A4LMNA
SCHEMBL19583457 0.93 NR3C1 (0.76) NR3C1PGRHIF1ACYP3A4LMNA
SCHEMBL4448853 0.92 NR3C1 (0.82) NR3C1PGRHIF1ACYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-12-16 — — US disclosed
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2025-02-27 — — US disclosed
CN-118955604-A Steroid compounds and antibody conjugates thereof 里珍纳龙药品有限公司 2024-11-15 — — CN disclosed
US-20240342299-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMA (US) 2024-10-17 — — US disclosed
US-12070506-B2 Steroids and antibody-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2024-08-27 — — US disclosed
CN-112004557-B Steroid compounds and antibody conjugates thereof 里珍纳龙药品有限公司 2024-07-30 — — CN disclosed
US-20230079407-A1 ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF REGENERON PHARMACEUTICALS, INC. 2023-03-16 — — US disclosed
US-11377502-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2022-07-05 — — US disclosed
US-11377502-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2022-07-05 — — US disclosed
WO-2019217591-A1 ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2019-11-14 — — WO disclosed
US-20190209702-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2019-07-11 — — US disclosed
WO-2019136487-A2 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2019-07-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190209702-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 NR3C1 2/4885PGR 223/4885HIF1A 3323/4885
US-20240342299-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 NR3C1 2/4885PGR 223/4885HIF1A 3323/4885
US-12070506-B2 Steroids and antibody-conjugates thereof SERPINA6, NR3C1, NR3C2 NR3C1 2/4885PGR 223/4885HIF1A 3323/4885
US-20230079407-A1 ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF CD47, MSR1, LDLR NR3C1 1628/4885PGR 3140/4885HIF1A 2218/4885
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 NR3C1 2/4885PGR 223/4885HIF1A 3323/4885
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR NR3C1 1628/4885PGR 3140/4885HIF1A 2218/4885
US-11377502-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR NR3C1 1628/4885PGR 3140/4885HIF1A 2218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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