Fluoranthene

Fluoranthene

SCHEMBL211527

[CH].c1ccc2c(c1)-c1cccc3cccc-2c13

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.94
HSD17B10 Q99714 7/20 0.94
MAPK1 P28482 4/20 0.94
TSHR P16473 4/20 0.94
ATM Q13315 2/20 0.94
L3MBTL1 Q9Y468 2/20 0.94
HPGD P15428 4/20 0.70
CASP1 P29466 3/20 0.70
CASP7 P55210 2/20 0.70
HIF1A Q16665 2/20 0.70
TP53 P04637 1/20 0.70
PABPC1 P11940 3/20 0.68
CYP3A4 P08684 2/20 0.68
DNMT1 P26358 2/20 0.68
CES2 O00748 1/20 0.57
BCHE P06276 1/20 0.57
CES1 P23141 1/20 0.57
MCL1 Q07820 1/20 0.57
TYMS P04818 2/20 0.52
KDM4E B2RXH2 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23525587 0.97 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL8873541 0.97 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL29355720 0.97 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL27152 0.97 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL29396242 0.97 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL28362492 0.94 ALDH1A1 (0.94) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL21326204 0.94 ALDH1A1 (0.94) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL29768792 0.94 ALDH1A1 (0.94) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL30911873 0.94 ALDH1A1 (0.94) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL29000576 0.94 ALDH1A1 (0.94) ALDH1A1HSD17B10MAPK1TSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-7968215-B2 OLED device with cyclobutene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2011-06-28 US disclosed
US-7931975-B2 Electroluminescent device containing a flouranthene compound GLOBAL OLED TECHNOLOGY LLC (US) 2011-04-26 US disclosed
US-20100141122-A1 OLED DEVICE WITH CYCLOBUTENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-06-10 US disclosed
US-20100117519-A1 ELECTROLUMINESCENT DEVICE CONTAINING A FLOURANTHENE COMPOUND GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100141122-A1 OLED DEVICE WITH CYCLOBUTENE ELECTRON INJECTION MATERIALS OCIAD1, JUND, OXER1 ALDH1A1 2071/4885HSD17B10 92/4885MAPK1 1448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.