Fluoranthene

Fluoranthene

SCHEMBL8873541

c1ccc2c(c1)-c1cccc3cccc-2c13.c1ccc2c(c1)-c1cccc3cccc-2c13

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
HSD17B10 Q99714 7/20 1.00
MAPK1 P28482 4/20 1.00
TSHR P16473 4/20 1.00
ATM Q13315 2/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
HPGD P15428 4/20 0.74
CASP1 P29466 3/20 0.74
CASP7 P55210 2/20 0.74
HIF1A Q16665 2/20 0.74
TP53 P04637 1/20 0.74
PABPC1 P11940 3/20 0.71
CYP3A4 P08684 2/20 0.71
DNMT1 P26358 2/20 0.71
CES2 O00748 1/20 0.60
BCHE P06276 1/20 0.60
CES1 P23141 1/20 0.60
MCL1 Q07820 1/20 0.60
TYMS P04818 2/20 0.55
KDM4E B2RXH2 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoranthene SCHEMBL27152 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL29396242 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRATM
SCHEMBL23525587 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL29355720 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL29768792 0.97 ALDH1A1 (0.94) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL21326204 0.97 ALDH1A1 (0.94) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL28362492 0.97 ALDH1A1 (0.94) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL30911873 0.97 ALDH1A1 (0.94) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL211527 0.97 ALDH1A1 (0.94) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL29000576 0.97 ALDH1A1 (0.94) ALDH1A1HSD17B10MAPK1TSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104772328-B A kind of biological prosthetic oil hydrocarbon compound contaminated soil method and application 黄晓东 2018-08-10 CN disclosed
CN-108339024-A A kind of method of harmful substance in removal plant extracts 湖南诺泽生物科技有限公司 2018-07-31 CN disclosed
CN-106645455-A Gas chromatography tandem mass spectrometry detection method for 18 polycyclic aromatic hydrocarbons in plastic products 中华人民共和国台州出入境检验检疫局 2017-05-10 CN disclosed
CN-105594008-A Material for organic electroluminescent elements, and organic electroluminescent element using same NIPPON STEEL & SUMIKIN CHEM CO 2016-05-18 CN disclosed
CN-104772328-A Method for biologically repairing soil polluted by petroleum hydrocarbon compounds and application HUANG XIAODONG 2015-07-15 CN disclosed
CN-103298849-B Oligofluoranthenes and methods and apparatuses for detecting nitroaromatics using the same UNIV TONGJI 2015-06-17 CN disclosed
CN-104458698-A Method for detecting organic pollutants by virtue of combination of solid phase micro-extraction and surface enhancement Raman UNIV SHANDONG 2015-03-25 CN disclosed
CN-102951991-B Condensed polycyclic compound and organic light emitting element including the same CANON KK 2015-03-04 CN disclosed
CN-101149359-B Solid phase micro-extraction probe and its analysis method for polycyclic aromatic hydrocarbon of environmental sample UNIV CHINA WEST NORMAL 2010-12-08 CN disclosed
CN-101149359-A Solid phase micro-extraction probe and its analysis method for polycyclic aromatic hydrocarbon of environmental sample UNIV CHINA WEST NORMAL (CN) 2008-03-26 CN disclosed
CN-1265744-C Method for producing diacetate fiber tows of chitosan modified cigarette SOUTH YANGTZE UNIVERSITY (CN) 2006-07-26 CN disclosed
CN-1561872-A Method for producing diacetate fiber tows of chitosan modified cigarette UNIV JIANGNAN (CN) 2005-01-12 CN disclosed
US-5600958-A Shipper HENNING STEVE (US) 1997-02-11 US disclosed