Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22475309 | 0.89 | ALDH1A1 (0.46) | MMEALDH1A1MMP8MMP2MMP9 | |
| SCHEMBL17948521 | 0.89 | ALDH1A1 (0.46) | MMEALDH1A1MMP8MMP2MMP9 | |
| SCHEMBL16168233 | 0.81 | MME (0.44) | MMEALDH1A1MMP8MMP2MMP9 | |
| SCHEMBL12214818 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MMP8MMP2MMP9KISS1R | |
| SCHEMBL13238863 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MMP8MMP2MMP9KISS1R | |
| SCHEMBL10036220 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MMP8MMP2MMP9KISS1R | |
| SCHEMBL18568836 | 0.80 | MME (0.36) | MMEMMP8MMP3 | |
| SCHEMBL26857870 | 0.79 | MMP3 (0.45) | ALDH1A1MMP9KISS1RMMP1MMP3 | |
| SCHEMBL26774818 | 0.79 | MMP3 (0.46) | ALDH1A1MMP8MMP9KISS1RMMP1 | |
| SCHEMBL15851259 | 0.79 | ALDH1A1 (0.50) | MMEALDH1A1MMP8MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136487-A2 | STEROIDS AND ANTIBODY-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |