SCHEMBL21153387

SCHEMBL21153387

C=NO[C@]1(C(=O)O)C[C@@H](O)C(NC(C)=O)C([C@H](O)[C@H](O)CO)O1

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NANP Q8TBE9 3/20 0.58
SELL P14151 1/20 0.48
SELP P16109 1/20 0.48
MAG P20916 3/20 0.46
SIGLEC7 Q9Y286 7/20 0.45
L3MBTL1 Q9Y468 1/20 0.43
CD22 P20273 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15128577 0.90 NANP (0.58) NANPSELLSELPMAGSIGLEC7
SCHEMBL29268869 0.88 NANP (0.61) NANPSELLSELPMAGSIGLEC7
SCHEMBL621891 0.88 NANP (0.59) NANPSELLSELPMAGSIGLEC7
SCHEMBL13125452 0.87 NANP (0.74) NANPSELLSELPMAGSIGLEC7
SCHEMBL7263212 0.87 NANP (0.62) NANPSELLSELPMAGSIGLEC7
SCHEMBL28161285 0.87 NANP (0.74) NANPSELLSELPMAGSIGLEC7
SCHEMBL2742889 0.87 NANP (0.74) NANPSELLSELPMAGSIGLEC7
SCHEMBL7066109 0.87 NANP (0.74) NANPSELLSELPMAGSIGLEC7
SCHEMBL8489507 0.87 NANP (0.74) NANPSELLSELPMAGSIGLEC7
SCHEMBL28106674 0.87 NANP (0.62) NANPSELLSELPMAGSIGLEC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190209697-A1 CELLS LABELLED WITH LIPID CONJUGATES AND METHODS OF USE THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190209697-A1 CELLS LABELLED WITH LIPID CONJUGATES AND METHODS OF USE THEREOF NPC1L1, CETP, LIPA NANP 1460/4885SELL 13/4885SELP 115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.