SCHEMBL621891

SCHEMBL621891

CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CO)O[C@](ON=[N+]=[N-])(C(=O)O)C[C@@H]1O

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NANP Q8TBE9 3/20 0.59
SIGLEC7 Q9Y286 7/20 0.51
SELL P14151 1/20 0.47
SELP P16109 1/20 0.47
NEU3 Q9UQ49 1/20 0.45
NEU2 Q9Y3R4 1/20 0.45
MAG P20916 3/20 0.45
CD22 P20273 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21153387 0.88 NANP (0.58) NANPSIGLEC7SELLSELPMAG
SCHEMBL15128577 0.88 NANP (0.58) NANPSIGLEC7SELLSELPMAG
SCHEMBL29268869 0.86 NANP (0.61) NANPSIGLEC7SELLSELPMAG
SCHEMBL7263212 0.85 NANP (0.62) NANPSIGLEC7SELLSELPMAG
SCHEMBL7066109 0.85 NANP (0.74) NANPSIGLEC7SELLSELPMAG
SCHEMBL13125452 0.85 NANP (0.74) NANPSIGLEC7SELLSELPMAG
SCHEMBL28161285 0.85 NANP (0.74) NANPSIGLEC7SELLSELPMAG
SCHEMBL2742889 0.85 NANP (0.74) NANPSIGLEC7SELLSELPMAG
SCHEMBL8489507 0.85 NANP (0.74) NANPSIGLEC7SELLSELPMAG
SCHEMBL28106674 0.85 NANP (0.62) NANPSIGLEC7SELLSELPMAG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12083186-B2 Methods for assembling scavenging particles NANOTICS, LLC (US) 2024-09-10 US disclosed
US-20240269319-A1 METHODS FOR ASSEMBLING SCAVENGING PARTICLES NANOTICS, LLC 2024-08-15 US disclosed
US-12048710-B2 Compositions and methods for modification of biomolecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-30 US disclosed
CN-118027177-A Diphenyl ring Xin Guijian albumin, albumin-antineoplastic compound nano particle and its preparation method and application 中山大学孙逸仙纪念医院 2024-05-14 CN disclosed
US-20240108662-A1 ENGINEERED CELLS FUNCTIONALIZED WITH IMMUNE CHECKPOINT MOLECULES AND USES THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2024-04-04 US disclosed
WO-2024064957-A2 GLYCOCAP: A CELL-FREE GLYCOSYLATION PLATFORM FOR CLICKABLE AZIDO-SIALOGLYCAN PRODUCTION NORTHWESTERN UNIVERSITY (US) 2024-03-28 WO disclosed
EP-4251738-A1 ENGINEERED CELLS FUNCTIONALIZED WITH IMMUNE CHECKPOINT MOLECULES AND USES THEREOF The University of North Carolina at Chapel Hill (US) 2023-10-04 EP disclosed
CN-116635405-A Engineering cell functionalized by immune checkpoint molecule and application thereof 北卡罗来纳大学教堂山分校 2023-08-22 CN disclosed
US-11684638-B2 Targeted delivery system, system components, and methods REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2023-06-27 US disclosed
CN-112656956-B Probe system suitable for in vivo fluorescence and PET imaging tracing of cells and preparation method 上海交通大学 2023-06-27 CN disclosed
US-7122703-B2 Chemoselective ligation THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-10-17 US disclosed
EP-1263771-B1 CHEMOSELECTIVE LIGATION BY USE OF A PHOSPHINE UNIV CALIFORNIA (US) 2006-06-14 EP disclosed
US-20060110782-A1 cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-05-25 US disclosed
WO-2006050262-A2 COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-05-11 WO disclosed
US-20050148032-A1 Chemoselective ligation THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2005-07-07 US disclosed
US-20030199084-A1 Chemoselective ligation THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-10-23 US disclosed
US-6570040-B2 Condensation of specifically engineered phosphine which can provide for formation of amide bond between two reactive partners resulting in product comprising a phosphine moiety or which can be engineered to comprise a cleavable linker THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-05-27 US disclosed
EP-1263771-A2 CHEMOSELECTIVE LIGATION BY USE OF A PHOSPHINE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2002-12-11 EP disclosed
US-20020016003-A1 Chemoselective ligation NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-02-07 US disclosed
WO-2001068565-A2 CHEMOSELECTIVE LIGATION BY USE OF A PHOSPHINE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12048710-B2 Compositions and methods for modification of biomolecules PTMS, QPCT, ANPEP NANP 478/4885SIGLEC7 148/4885SELL 853/4885
US-20020016003-A1 Chemoselective ligation PTMS, QPCT, DNPEP NANP 396/4885SIGLEC7 583/4885SELL 637/4885
US-20030199084-A1 Chemoselective ligation PTMS, QPCT, DNPEP NANP 396/4885SIGLEC7 583/4885SELL 637/4885
US-20050148032-A1 Chemoselective ligation PTMS, QPCT, DNPEP NANP 396/4885SIGLEC7 583/4885SELL 637/4885
US-20060110782-A1 cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling PTMS, QPCT, DNPEP NANP 215/4885SIGLEC7 200/4885SELL 950/4885
US-20240108662-A1 ENGINEERED CELLS FUNCTIONALIZED WITH IMMUNE CHECKPOINT MOLECULES AND USES THEREOF CD274, PDCD1LG2, PDCD1 NANP 474/4885SIGLEC7 113/4885SELL 116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.