Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL211215 | 0.95 | CSNK2A2 (0.39) | CSNK2A2CSNK2A1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL211918 | 0.94 | RXFP1 (0.40) | CSNK2A2CSNK2A1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL213354 | 0.94 | KDM4E (0.43) | CSNK2A2CSNK2A1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL211757 | 0.94 | CSNK2A2 (0.41) | CSNK2A2CSNK2A1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL212054 | 0.94 | CSNK2A2 (0.38) | CSNK2A2CSNK2A1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL213263 | 0.94 | KDM4E (0.45) | CSNK2A2CSNK2A1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL212239 | 0.94 | CSNK2A2 (0.38) | CSNK2A2CSNK2A1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL211530 | 0.92 | CSNK2A2 (0.37) | CSNK2A2CSNK2A1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL213581 | 0.90 | CSNK2A2 (0.42) | CSNK2A2CSNK2A1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL213026 | 0.89 | RAB9A (0.45) | CSNK2A2CSNK2A1KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |