Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.68 |
| ▸ | CCR4 | P51679 | 6/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | DNM2 | P50570 | 2/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | STK17B | O94768 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20154728 | 0.81 | STK17A (1.00) | STK17ASCN9ASTK17B | |
| SCHEMBL2272514 | 0.76 | MEN1 (0.53) | CCR4KCNH2CDK1SLC2A1 | |
| SCHEMBL3439824 | 0.74 | CDK1 (0.59) | STK17ACCR4IGF1RDNM2CDK4 | |
| SCHEMBL379222 | 0.74 | AURKA (0.69) | STK17ACDK4CDK2SYKSCN9A | |
| SCHEMBL1917372 | 0.74 | STK17A (0.73) | STK17ASTK17B | |
| SCHEMBL14021247 | 0.74 | JAK2 (0.66) | IGF1RCDK2 | |
| SCHEMBL18930076 | 0.74 | TLR8 (0.47) | CCR4DNM2CDK1KDR | |
| SCHEMBL3439836 | 0.72 | CDK1 (0.56) | STK17ACCR4IGF1RDNM2CDK4 | |
| SCHEMBL22508313 | 0.72 | STK17A (0.73) | STK17ASYKSTK17B | |
| SCHEMBL22508341 | 0.71 | STK17A (0.76) | STK17ACDK4CDK2SYKSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158641-B2 | 2-anilino-4-aminoalkyleneaminopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-17 | — | — | US | claimed |