Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24476307 | 0.90 | CA2 (0.51) | CA2CTSSCTSKMEN1KMT2A | |
| SCHEMBL22300573 | 0.90 | CA2 (0.51) | CA2CTSSCTSKMEN1KMT2A | |
| SCHEMBL25689756 | 0.86 | CA2 (0.48) | CA2CTSSCTSKMEN1KMT2A | |
| SCHEMBL23543192 | 0.85 | CA2 (0.38) | CA2CTSSCTSKMEN1KMT2A | |
| SCHEMBL19277932 | 0.84 | MEN1 (0.56) | CA2CTSSCTSKMEN1KMT2A | |
| SCHEMBL25993767 | 0.84 | MEN1 (0.56) | CA2CTSSCTSKMEN1KMT2A | |
| SCHEMBL22815478 | 0.84 | MEN1 (0.56) | CA2CTSSCTSKMEN1KMT2A | |
| SCHEMBL19391315 | 0.84 | MEN1 (0.56) | CA2CTSSCTSKMEN1KMT2A | |
| SCHEMBL19391314 | 0.84 | MEN1 (0.56) | CA2CTSSCTSKMEN1KMT2A | |
| SCHEMBL3218237 | 0.83 | CA1 (0.48) | CA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217591-A1 | ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-11-14 | — | — | WO | disclosed |
| WO-2019136487-A2 | STEROIDS AND ANTIBODY-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |