SCHEMBL21154495

SCHEMBL21154495

O=NCCCN1CCN(CCO)CC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 1/20 0.43
CHRM2 P08172 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
CHRM1 P11229 1/20 0.41
DRD2 P14416 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
DRD1 P21728 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2A P28223 1/20 0.41
SLC6A4 P31645 1/20 0.41
ADRA1A P35348 1/20 0.41
HRH1 P35367 1/20 0.41
OPRM1 P35372 1/20 0.41
DRD3 P35462 1/20 0.41
CACNA1B Q00975 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23719581 0.86 ALDH1A1 (0.46) ALDH1A1KDM4EKMT2AMEN1CYP3A4
SCHEMBL11086634 0.79 HRH3 (0.52) ALDH1A1HRH3MAPK1SMN1; SMN2LMNA
SCHEMBL16549913 0.77 HRH3 (0.56) ALDH1A1SIGMAR1HRH3MAPK1SMN1; SMN2
SCHEMBL17493163 0.77 HRH3 (0.55) ALDH1A1KDM4ECHRM2HTR1AADRA2A
SCHEMBL22911174 0.76 ALDH1A1 (0.54) ALDH1A1KDM4ECHRM2HTR1AADRA2A
SCHEMBL1314968 0.76 ALDH1A1 (0.54) ALDH1A1KDM4ECHRM2HTR1AADRA2A
SCHEMBL154974 0.75 ALDH1A1 (0.65) ALDH1A1KDM4ECHRM2HTR1AADRA2A
SCHEMBL3971866 0.75 ALDH1A1 (0.65) ALDH1A1KDM4ECHRM2HTR1AADRA2A
SCHEMBL235856 0.75
SCHEMBL13833159 0.75 ALDH1A1 (0.65) ALDH1A1KDM4ECHRM2HTR1AADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3508538-A1 INK-JET INK COMPOSITION AND IMAGE FORMATION METHOD FUJIFILM Corporation (JP) 2019-07-10 EP disclosed