Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16549913 | 0.98 | HRH3 (0.56) | HRH3CYP1A2MAPK1SMN1; SMN2MAPT | |
| SCHEMBL19720787 | 0.84 | — | — | |
| SCHEMBL12785747 | 0.82 | LMNA (0.52) | HRH3CYP1A2MAPK1SMN1; SMN2MAPT | |
| SCHEMBL3439938 | 0.81 | HRH3 (0.75) | HRH3CYP1A2MAPK1SMN1; SMN2MAPT | |
| SCHEMBL18034154 | 0.79 | CXCR4 (0.55) | HRH3CYP1A2SMN1; SMN2LMNACXCR4 | |
| SCHEMBL5980656 | 0.79 | SMN1; SMN2 (0.54) | CYP1A2MAPK1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL21154495 | 0.79 | ALDH1A1 (0.43) | HRH3MAPK1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL5911234 | 0.79 | HRH3 (0.65) | HRH3CYP1A2MAPK1SMN1; SMN2MAPT | |
| SCHEMBL23828672 | 0.78 | HRH3 (0.81) | HRH3CYP1A2MAPK1SMN1; SMN2MAPT | |
| SCHEMBL433324 | 0.78 | HRH3 (0.81) | HRH3CYP1A2MAPK1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108986-A1 | N-substituted flavone-8-carboxamides | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1984-05-23 | — | — | EP | disclosed |