Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 5/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27979216 | 0.75 | EPHX2 (0.38) | KDM1AMAOAMAOB | |
| SCHEMBL14351479 | 0.70 | TDP1 (0.33) | — | |
| SCHEMBL5269898 | 0.69 | GBA1 (0.50) | — | |
| SCHEMBL27689141 | 0.69 | GBA1 (0.50) | — | |
| SCHEMBL24478131 | 0.69 | — | — | |
| SCHEMBL14351586 | 0.68 | TSHR (0.30) | — | |
| Iodide SCHEMBL3513621 | 0.68 | HIF1A (0.38) | CNR1CNR2TLR7KDM1AMAOA | |
| Hydrochloric Acid SCHEMBL8555351 | 0.66 | CCR3 (0.58) | — | |
| SCHEMBL23733125 | 0.66 | CA12 (0.30) | — | |
| SCHEMBL13033253 | 0.66 | CNR1 (0.35) | CNR1CNR2TLR7KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136145-A1 | PRINS REACTION AND COMPOUNDS USEFUL IN THE SYNTHESIS OF HALICHONDRIN MACROLIDES AND ANALOGS THEREOF | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-07-11 | — | — | WO | disclosed |