Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27689141 | 1.00 | GBA1 (0.50) | GBA1TSHRCCR3LMNASMN1; SMN2 | |
| (Z)-1,2-Diphenylethene SCHEMBL23411669 | 0.90 | LMNA (0.46) | GBA1TSHRCCR3LMNASMN1; SMN2 | |
| SCHEMBL2931658 | 0.89 | GBA1 (0.47) | GBA1TSHRCCR3LMNASMN1; SMN2 | |
| SCHEMBL5522664 | 0.88 | GBA1 (0.59) | GBA1TSHRCCR3LMNASMN1; SMN2 | |
| SCHEMBL23411667 | 0.87 | GBA1 (0.40) | GBA1TSHRCCR3LMNASMN1; SMN2 | |
| SCHEMBL16572184 | 0.83 | GBA1 (0.52) | GBA1TSHRCCR3PRMT3CARM1 | |
| SCHEMBL29991411 | 0.81 | ALDH1A1 (0.45) | TSHRNPSR1GRIN2B | |
| SCHEMBL28066111 | 0.81 | TSHR (0.53) | GBA1TSHRCCR3LMNASMN1; SMN2 | |
| SCHEMBL30476131 | 0.81 | ALDH1A1 (0.45) | TSHRNPSR1GRIN2B | |
| SCHEMBL24348217 | 0.77 | NAMPT (0.36) | CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856125-A1 | PROTEASE INHIBITOR PRECURSOR SYNTHESIS | Tibotec Pharmaceuticals Ltd. (IE) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006089942-A1 | PROTEASE INHIBITOR PRECURSOR SYNTHESIS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2006-08-31 | — | — | WO | disclosed |