Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12934412 | 0.80 | EPHX2 (0.40) | EPHX2RAB9ANPC1EPHX1KDM1A | |
| SCHEMBL1710517 | 0.80 | MEN1 (0.46) | KDM1AMAOAMAOBALDH1A1KMT2A | |
| SCHEMBL1710651 | 0.78 | MEN1 (0.43) | ALDH1A1KMT2A | |
| SCHEMBL13459844 | 0.77 | PRMT6 (0.36) | NPC1OPRM1 | |
| SCHEMBL21155168 | 0.75 | CNR1 (0.34) | KDM1AMAOAMAOB | |
| SCHEMBL3435515 | 0.74 | DRD2 (0.39) | OPRM1 | |
| Hydrochloric Acid SCHEMBL8555351 | 0.74 | CCR3 (0.58) | SIGMAR1ALDH1A1 | |
| SCHEMBL3388478 | 0.73 | TLR4 (0.37) | SIGMAR1ALDH1A1 | |
| SCHEMBL3385701 | 0.73 | OPRM1 (0.36) | OPRM1 | |
| SCHEMBL3388474 | 0.73 | TLR4 (0.37) | SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102203058-B | Sulfur-linked compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC | 2014-11-12 | — | — | CN | disclosed |