Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18883311 | 0.89 | SMN1; SMN2 (0.43) | POLBRXFP1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL26295068 | 0.87 | HSD17B2 (0.41) | POLBRXFP1SMN1; SMN2APEX1KDM4E | |
| SCHEMBL17706660 | 0.86 | POLB (0.41) | POLBRXFP1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL12780726 | 0.83 | PKM (0.45) | POLBRXFP1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL12091348 | 0.83 | MMP2 (0.48) | POLBRXFP1SMN1; SMN2GAAHTT | |
| SCHEMBL12190621 | 0.82 | PKM (0.50) | POLBGAAKEAP1NFE2L2KDM4E | |
| SCHEMBL19391856 | 0.80 | HTT (0.39) | POLBRXFP1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL12780764 | 0.80 | PKM (0.51) | POLBGAAKEAP1NFE2L2KDM4E | |
| SCHEMBL26945108 | 0.79 | HSD17B2 (0.38) | POLBRXFP1SMN1; SMN2APEX1ALDH1A1 | |
| SCHEMBL12780798 | 0.79 | PKM (0.58) | POLBSMN1; SMN2GAAKDM4EMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190209973-A1 | MULTILAYER HOLLOW FIBRE MEMBRANES | BASF SE (DE) | 2019-07-11 | — | — | US | disclosed |